Guide

Peptide Cycle Guide

A "cycle" is a defined run of a peptide followed by reassessment or time off. Lengths vary widely by compound and goal.

Start low, go slow

Begin at the conservative end, judge tolerance for several days, and only increase if needed. Incretins such as Semaglutide, Tirzepatide, and Retatrutide follow a weekly titration schedule shown on each page.

Cycle length and breaks

Short-acting pulses and recovery peptides are often run in defined blocks with time off; review each peptide page for its specific cycle-length guidance and reassess rather than running indefinitely.

Plan the dose

Use the calculator to convert each step of a titration into a syringe draw, and the categories to compare similar options.

Build a goal-based peptide planPrintable protocol sheet coming soon.